Transcription factor Sp1 (specificity factor 1) was traditionally viewed as a basal transcription factor responsible for the regulation of housekeeping genes. However, recent data have indicated that Sp1 is an important player in the DNA damage response (DDR), controlling cellular life/death decisions in the … Zobraziť viac As mentioned earlier, many cancer cells overexpress Sp1, which correlates with poor patient survival. Moreover, downregulation of Sp1 leads to decreased … Zobraziť viac A better understanding of the molecular mechanisms involved in genomic integrity checkpoint may explain how physiological populations of healthy … Zobraziť viac Web4. apr 2024 · Summary. The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved …
Sp1/Sp3 transcription factors regulate hallmarks of …
WebInterestingly, the function of SP3, a protein related to SP1 with similar DNA binding specificity, depends on the number of SP1 binding motifs in the promoter. SP3 works as an activator for promoters containing a single SP1 binding motif, but it represses transcription from promoters containing multiple SP1 binding motifs by inhibiting SP1 ... WebThe sphingosine-1-phosphate receptors regulate fundamental biological processes such as cell proliferation, angiogenesis, migration, cytoskeleton organization, endothelial cell … credit checks an international business
The role of Sp1 in the detection and elimination of cells …
WebSP1. A gene on chromosome 12q13.1 that encodes a transcription factor which up- or downregulates transcription in response to physiological and pathological stimuli. SP1 … WebThe new version V1.0 SP1 can be parallelly installed with V1.0.0, imported to TIA portal and update the Project library and the instances with TIA portal “Update types” function. To upgrade the Unified faceplate types (block symbol and faceplates), user must delete the WebSIMATIC BATCH blocks V9.0 SP1 Function Manual, 11/2024, A5E38209995-AB 5. Table of contents SIMATIC BATCH blocks V9.0 SP1 6 Function Manual, 11/2024, A5E38209995-AB. Security information 1 Siemens provides products and solutions with industrial security functions that support the buckingham upholstery