Web11 aug. 2024 · Mitophagy is a specific autophagic phenomenon in which damaged or redundant mitochondria are selectively cleared by autophagic lysosomes. A decrease in mitophagy can accelerate the aging process. Mitophagy is related to health and longevity and is the key to protecting stem cells from metabolic stress damage. Web6 feb. 2024 · Mitochondria are crucial for the regulation of intracellular energy metabolism, biosynthesis, and cell survival. And studies have demonstrated the role of mitochondria in oxidative stress–induced autophagy in plants. Previous studies found that waterlogging stress can induce the opening of mitochondrial permeability transition pore (mPTP) and …
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Web4 apr. 2024 · Autophagy-mediated degradation of mitochondria (mitophagy) is a key process in cellular quality control. Although mitophagy impairment is involved in several patho-physiological conditions,... Web11 apr. 2024 · Urolithin A (UA) is a natural dietary, microflora-derived metabolite shown to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging¹. passiflora curarina tropfen
Mitophagy Contributes to the Pathogenesis of Inflammatory
WebSustained perturbation of ΔΨm, which is normally tightly controlled to ensure cell proliferation and survival, triggers various stress pathways as part of the cellular … Web20 okt. 2024 · In summary, oocytes do contain regulators of mitophagy, but oocytes cannot actively induce mitophagy to clear damaged mitochondria under normal circumstances. However, oocyte mitophagy can be initiated under the action of drugs or abnormal environmental stimuli, and affect the developmental ability of oocytes. Web20 apr. 2024 · Because the uncoupling of OXPHOS in the mitochondria is known to induce mitophagy, 46 we tested whether Baf A1 induces mitophagy by assessing the expression of the mitophagy protein PTEN-induced kinase-1 (PINK-1) in normoxic conditions. 47 Carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial uncoupler, was … passiflora biancospino melissa e valeriana