Cisplatin review

Author: xmwc

August undefined, 2024

WebOct 13, 2024 · In this Review, we provide an overview of the mechanisms that underlie cisplatin-induced AKI and CKD and discuss the therapeutic implications of potential … WebCisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can cause acute kidney injury and chronic kidney disease. Preclinical studies have provided insights into the cellular …

Cisplatin Uses, Side Effects & Warnings - Drugs.com

WebMay 24, 2006 · Background Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the rare complications associated with its use. Case presentation A 42- year-old woman presented with a 20 year-history of hypokalemic metabolic alkalosis with … WebSep 21, 2016 · Cisplatin produced superior response rates and survival in head and neck cancers. There are no published randomized phase III studies of bladder, cervical, endometrial, and esophageal cancers. CONCLUSION: Carboplatin does not possess equivalent activity to cisplatin in all platinum-sensitive tumors. cite this for me 7th

Cisplatin and AKI: an ongoing battle with new perspectives

WebCisplatin or (SP-4-2)-diamminedichloridoplatinum(II) is one of the most potential and widely used drugs for the treatment of various solid cancers such as testicular, ovarian, head and neck, bladder, lung, cervical cancer, melanoma, lymphomas and several others. Cisplatin exerts anticancer activity … WebOct 5, 2014 · Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known chemotherapeutic drug. It has been used for treatment of numerous human cancers including bladder, head and neck, lung, ovarian, and testicular cancers. It is effective against various types of cancers, including carcinoma … WebCisplatin Nephrotoxicity: A Review XIN YAO, MD; KESSARIN PANICHPISAL, MD; NEIL KURTZMAN, MD; KENNETH NUGENT, MD ABSTRACT: Background: Cisplatin is a major antineo-plastic drug for the treatment of solid tumors, but it has dose-dependent renal toxicity. Methods: We reviewed clinical and experimental literature on cisplatin nephro- diane sawyer china products

Cisplatin: The first metal based anticancer drug - PubMed

Emerging and established therapies for chemotherapy-induced

WebAug 1, 2007 · Cisplatin is a major antineoplastic drug used for the treatment of solid tumors. Its chief dose-limiting side effect is nephrotoxicity; 20% of patients receiving high-dose cisplatin have severe renal dysfunction. Cisplatin-DNA crosslinks cause cytotoxic lesions in tumors and other dividing cells. WebSep 18, 2024 · NCBI Bookshelf diane sawyer contact informationWebMost voted positive review. 39 People found this comment helpful . Stage three cancer at base of tongue. Now 45 months in remission. Received 62 radiation and 21 hrs of … cite this for me apa 7 bib

"WebJul 22, 2024 · Cisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum … " - Cisplatin review

Cisplatin review

WebConcurrent cisplatin-based chemoradiotherapy versus exclusive radiotherapy in high-risk cervical cancer: a meta-analysis Xiang-Yu Meng,1,* Yi Liao,2,* Xiao-Ping Liu,3 Sheng Li,1 Ming-Jun Shi,4 Xian-Tao Zeng11Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, People’s Republic of …

Did you know?

WebNational Center for Biotechnology Information WebMar 15, 2024 · Cisplatin has not yet been recognized as a potential trigger for recall reactions. Although it was part of several reported multidrug trigger combinations, all review works referred to cisplatin as not suspicious, suggesting the combination partner as the effector. We performed a focused systematic literature review aiming to re-evaluate the ...

WebDec 12, 2024 · A recent systematic review and meta-analysis published in 2024 by Li et al. studied the effect of mannitol on cisplatin-induced nephrotoxicity. A total of 4168 patients were included and results showed that mannitol has the best effect at doses of cisplatin lower than 75 mg/m 2. WebSep 9, 2014 · Cisplatin is a common and effective cancer drug. It has revolutionized the treatment of advanced germ cell tumors which were previously considered highly fatal.1-3Side effects (including peripheral neuropathy) and acquired resistance unfortunately have limited its use4and paved the way for the development of new compounds.

WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different … WebAug 1, 2007 · Cisplatin induces magnesium depletion, and magnesium deficiency itself may enhance cisplatin nephrotoxicity. Cisplatin treatment often produces extensive gastrointestinal side effects, which. Summary. In this review, we focus on the pathophysiology of toxic renal injury caused by an important chemotherapeutic agent.

WebFeb 1, 1989 · Background: Cisplatin is a major antineo- plastic drug for the treatment of solid tumors, but it has dose-dependent renal toxicity. Methods: We reviewed clinical and experimental literature on...

WebA systematic review was performed to evaluate clinical studies that have examined hydration and supplementation strategies to prevent cisplatin-induced nephrotoxicity. … cite this for me anglia ruskin harvardWebJun 24, 2011 · Interstrand crosslinks (ICLs) are a type of DNA damage that is induced by various chemotherapeutics, such as cisplatin. This Review discusses how these lesions are repaired through multiple ... diane sawyer chevroletWebOct 23, 2003 · Cisplatin is a neutral inorganic, square planar complex that reacts with DNA to induce its characteristic biological effects, which culminate in either repair of the DNA damage and cell survival... diane sawyer fashions nylon boots high heelsWebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), … diane sawyer college majorWebThis review covered the hallmarks of inflammation common and distinct between different CITs, the role of innate immune components in development of CITs, as well as current … diane sawyer fashions and accessories 66WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … diane sawyer faceliftWebJul 12, 2007 · Cisplatin is a very effective cancer drug and has had a major clinical impact, particularly for patients with testicular or ovarian cancers. But, it is notoriously toxic to the kidneys... cite this for me asme